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Table 2 Univariate and multivariate Cox regression analyses estimating the risk factors of PFS in thymoma patients

From: Prognostic factors in patients with thymoma who underwent surgery

Variable

Univariate analyses

Multivariate analyses

HR

95% CI

P value

HR

95% CI

P value

Age

1.153

0.474 ~ 2.807

0.754

   

Gender

1.936

0.853 ~ 4.391

0.114

   

KPS

1.647

0.736 ~ 3.681

0.224

   

Smoking

2.376

1.080 ~ 5.227

0.031

2.989

1.142 ~ 7.823

0.026

Myasthenia gravis

1.043

0.448 ~ 2.429

0.922

   

Surgical approach

3.426

1.348 ~ 8.704

0.01

0.838

0.171 ~ 4.099

0.827

Tumor size

5.597

2.062 ~ 15.193

0.001

4.871

1.166 ~ 20.352

0.030

Resection status

7.941

2.942 ~ 21.432

 < 0.001

0.888

0.108 ~ 7.289

0.912

WHO classification

3.595

2.010 ~ 6.428

 < 0.001

2.333

0.903 ~ 6.025

0.080

Masaoka-Koga stage

10.268

3.486 ~ 30.250

 < 0.001

2.603

0.240 ~ 28.231

0.432

Ki-67

1.240

0.488 ~ 3.151

0.651

   

Neutrophil

1.672

0.704 ~ 3.968

0.244

   

NLR

1.841

0.709 ~ 4.777

0.210

   

Adjuvant radiotherapy

6.094

2.267 ~ 16.379

 < 0.001

2.253

0.572 ~ 8.876

0.246

Adjuvant chemotherapy

7.407

3.223 ~ 17.024

 < 0.001

2.631

0.688 ~ 10.056

0.157

  1. Abbreviations: PFS progression-free survival, HR hazard ratio, CI confidence interval, KPS Karnofsky Performance Status Scale, WHO World Health Organization, NLR neutrophil-to-lymphocyte ratio