Table 4 The results of univariate and multivariate Cox regression analysis include clinical factors and risk scores in three sets

Training set

 Age

1.03

1.02-1.05

<0.001

1.03

1.02-1.05

<0.001

 Gender

0.90

0.58-1.38

0.630

0.90

0.57-1.42

0.642

 Grade

0.99

0.74-1.33

0.955

1.05

0.74-1.48

0.795

  T

1.29

1.05-1.58

0.015

1.16

0.92-1.47

0.215

  N

1.48

1.20-1.83

<0.001

1.45

1.11-1.90

0.006

Risk score

2.25

1.89-2.68

<0.001

2.12

1.76-2.56

<0.001

Test set

 Age

1.01

0.99-1.03

0.483

0.99

0.97-1.02

0.582

 Gender

0.59

0.35-0.99

0.045

0.60

0.34-1.06

0.081

 Grade

1.42

0.94-2.13

0.095

1.43

0.92-2.22

0.109

  T

1.21

0.93-1.55

0.149

0.98

0.73-1.30

0.878

  N

1.30

0.98-1.65

0.075

1.22

0.92-1.61

0.168

Risk score

1.58

1.33-1.87

<0.001

1.53

1.28-1.83

<0.001

Whole set

 Age

1.02

1.01-1.04

<0.001

1.02

1.00-1.03

0.016

 Gender

0.76

0.55-1.06

0.101

0.93

0.65-1.33

0.691

 Grade

1.12

0.88-1.42

0.357

1.11

0.86-1.44

0.425

  T

1.27

1.08-1.49

0.004

1.05

0.88-1.26

0.574

  N

1.38

1.17-1.63

<0.001

1.31

1.10-1.57

0.003

Risk score

1.78

1.59-1.99

<0.001

1.66

1.48-1.87

<0.001