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Table 4 Two-step multivariate analysis of the prognostic factors for non-pCR patients with colorectal cancer

From: Significance of ypTNM stage in determining the prognosis and therapy after surgery for locally advanced rectal cancer

 

Hazard ratio

95% CI

P

Step 1

 Histological differentiation

  

0.069

 Clinical TNM stage

1.811

1.084–3.025

0.023*

Step 2

 Clinical TNM stage

  

0.974

 Neoadjuvant pathologic TNM stage

2.704

1.811–4.038

 < 0.001*

  1. Step 1, with consideration of all significantly important prognostic factors in univariate analysis except for neoadjuvant pathologic TNM stage after surgery
  2. Step 2, with consideration of clinical TNM stage and neoadjuvant pathologic TNM stage in univariate analysis
  3. *statistical significance