Fig. 9

Histopathology of duodenal biopsy specimens. Hematoxylin and eosin staining (A) and Alcian blue-periodic acid Schiff (AB-PAS) staining (B). Poorly differentiated adenocarcinoma (PDA) with scattered signet-ring cell-like cells is observed (A). Signet-ring cell-like cells have enriched intracytoplasmic mucin, and most PDA-like cells also have more intracytoplasmic mucin than the original PDA cells (B). A, B Original magnification × 400. Each bar displayed at the bottom right indicates 100 μm