Fig. 10From: Histological transformation to signet-ring cell carcinoma in a patient with clinically aggressive poorly differentiated adenocarcinoma of the ascending colon after response to chemotherapy plus cetuximab: a case reportRepresentative histopathology and immunostaining of autopsy specimens. Hematoxylin and eosin staining (A pancreas head, B lymph node near left adrenal gland), Alcian blue-periodic acid Schiff (AB-PAS) staining (C), and immunostaining for CK20 (D), CDX2 (E), SATB2 (F), and CK7 (G). Signet-ring cell-like cells are proliferating and infiltrating (A and B). These cells have enriched intracytoplasmic mucin (C) and are positive for CK20 (D), CDX2 (E) and SATB2 (F) and negative for CK7 (G). A–G Original magnification × 400. Each bar displayed at the bottom right indicates 100 μmBack to article page