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Table 2 Univariate analysis of overall survival in patients with PBSA and SBAB

From: Clinicopathological analysis and prognostic treatment study of angiosarcoma of the breast: a SEER population-based analysis

 

Primary angiosarcoma

Secondary angiosarcoma

Median OS, mo

95%CI

p value

Median OS, mo

95%CI

p value

Median age

  < 65

39

20.779–57.221

 

NA

NA

 

  ≥ 65

33

23.505–42.495

p = 0.845

35

18.651–51.349

p = 0.018

Race

 White

36

23.705–48.295

 

42

29.668–54.332

 

 Non-white

39

11.243–66.757

p = 0.763

19

13.500–24.500

p = 0.456

Site

 Central

31

0.594–61.406

 

48

0–114.644

 

 Inner quadrant

NA

NA

 

22

0–62.564

 

 Outer quadrant

52

21.747–79.253

 

NA

NA

 

 Overlap

31

17.658–44.342

 

29

16.868–41.132

 

 NOS

34

14.474–53.526

p = 0.303

29

13.545–44.455

p = 0.151

Grade

 G1

38

12.245–63.755

 

NA

NA

 

 G2

73

39.724–106.276

 

29

25.277–32.723

 

 G3

19

0–40.336

 

42

16.790–67.210

 

 Gx

31

23.793–38.207

p = 0.149

29

9.757–48.243

p = 0.042

Tumor size

  < 5 cm

143

24.180–261.820

 

57

36.842–77.158

 

 5–10 cm

32

24.558–39.443

 

29

12.806–45.194

 

  > 10 cm

13

5.296–20.704

p < 0.001

22

12.833–31.167

p = 0.078

Tumor spread

 Regional

32

16.347–47.653

 

26

13.191–38.809

 

 Localized

48

28.395–67.605

 

76

NA

 

 Distant

4

0–9.544

p < 0.001

7

0–14.201

p < 0.001

Tumor extension

 Confined

38

19.424–56.576

 

76

NA

 

 Local infiltration

32

13.406–50.544

 

40

17.095–62.905

 

 Deep

31

0–64.447

p = 0.773

17

11.887–22.113

p < 0.001

Total number

 1–2

37

24.285–49.715

 

42

27.111–56.889

 

  ≥ 3

38

NA

p = 0.303

29

1.867–56.133

p = 0.527

Chemotherapy

 Yes

37

26.769–47.231

 

29

11.371–46.629

 

 No

38

24.961–51.039

p = 0.650

45

29.575–60.425

p = 0.737

Radiation

 Yes

39

5.274–72.726

 

35

3.630–66.370

 

 No

36

21.980–50.020

p = 0.284

45

29.076–60.924

p = 0.684

Surgery

 Unknow

14

0–30.003

 

11

NA

 

 Partial mastectomy

NA

NA

 

35

5.868–64.132

 

 Mastectomy

32

28.273–35.727

p = 0.002

42

27.504–56.496

p = 0.155