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Table 2 Incidence of ovarian metastasis according to each risk factor

From: Impacts of ovarian preservation on the prognosis of neuroendocrine cervical carcinoma: a retrospective analysis based on machine learning

Variable

Total, n = 86

OM, n

%

P

Age (%)

1

  ≤ 46

34

1

2.94

 

  > 46

52

2

3.85

 

FIGO stage (%)

0.001

 I

48

0

0.00

 

 II

11

1

9.09

 

 III

25

1

4.00

 

 IV

2

1

50.00

 

Tumor size (%)

1

  ≤ 2.4 cm

19

0

0.00

 

  > 2.4 cm

57

1

1.75

 

Histological heterogeneity (%)

0.771

 Pure

36

2

5.56

 

 Mix

50

1

2.00

 

 Mix

   

1

  NEC differentiation

7

0

0.00

 

  NECC dominant

43

1

2.33

 

 Mix

   

0.880

  Squamous

9

0

0.00

 

  Adenocarcinoma

40

1

2.50

 

  Both

1

0

0.00

 

LNM (%)

0.448

 Negative

60

1

1.67

 

 Positive

26

2

7.69

 

 Positive

   

0.015

  Pelvic

22

0

0.00

 

  Pelvic & para-aortic

4

2

50.00

 

 Positive

   

0.330

  LNM ratio low

15

0

0.00

 

  LNM ratio high

11

2

18.18

 

Parametrial involvement (%)

0.050

 Negative

75

1

1.33

 

 Positive

11

2

18.18

 

Vaginal invasion (%)

0.332

 Negative

63

1

1.59

 

 Positive

22

2

9.09

 

Incisal margin (%)

0.383

 Negative

78

1

1.28

 

 Positive

7

1

14.29

 

LUSI (%)

0.264

 Negative

66

1

1.52

 

 Positive

20

2

10.00

 

DIM (%)

0.588

 Superficial 1/3

20

0

0.00

 

 Middle 1/3

26

1

3.85

 

 Deep 1/3

38

2

5.26

 

LVSI (%)

1

 Negative

13

0

0.00

 

 Positive

69

3

4.35

 
  1. Abbreviations: OM Ovarian metastasis, FIGO International Federation of Gynecology and Obstetrics, NEC Neuroendocrine carcinoma, NECC High-grade neuroendocrine cervical carcinoma, LNM Lymph node metastasis, LUSI Lower uterine segment involvement, DIM Depth of myometrial invasion, LVSI Lymph-vascular space invasion