Table 3 Univariate and multivariate analysis of overall survival and disease-free survival

Age (> 63/ ≤ 63 years)

2.384 (0.914–6.219)

0.076

1.418 (0.597–3.369)

0.428

Gender (male/female)

0.723 (0.299–1.748)

0.472

0.880 (0.365–2.125)

0.777

Hb level (≥ 120/ < 120)

1.520 (0.616–3.749)

0.363

2.133 (0.858–5.303)

0.103

Alb level (≥ 40/ < 40)

1.222 (0.439–3.406)

0.701

1.472 (0.530–4.084)

0.458

CEA level (> 5/ ≤ 5)

1.143 (0.377–3.467)

0.813

0.866 (0.300–2.500)

0.790

CA19-9 level (> 37/ ≤ 37)

1.554 (0.425–5.680)

0.505

0.902 (0.202–4.036)

0.893

ASA physical status (III/I-II)

2.376 (0.785–7.190)

0.126

2.049 (0.602–6.977)

0.251

Operative approach (laparoscopy/open)

1.658 (0.626–4.394)

0.309

1.278 (0.511–3.199)

0.600

Type of surgical resection (EXT/LHS)

0.725 (0.240–2.188)

0.568

0.836 (0.275–2.543)

0.752

0.828 (0.303–2.267)

0.713

0.836 (0.305–2.292)

0.727

Tumor differentiation (poor/well- moderate)

1.721 (0.711–4.166)

0.228

1.692 (0.709–4.037)

0.236

Tumor size (> 5/ ≤ 5 cm)

1.271 (0.516–3.132)

0.602

0.899 (0.378–2.139)

0.811

T stage (T3-T4/T1-T2)

1.672 (0.222–12.583)

0.618

1.880 (0.251–14.055)

0.539

N stage

 N0

-

-

-

-

-

-

-

-

 N1

10.952 (1.401–85.584)

0.023

10.899 (1.394–85.190)

0.023

13.462 (1.736–104.358)

0.013

13.461 (1.736–104.353)

0.013

 N2

29.321 (3.699–232.448)

0.001

28.923 (3.643–229.610)

0.001

32.330 (4.067–256.983)

0.001

32.288 (4.062–256.630)

0.001