Table 3 Univariate analysis of prognostic factors in patients with stage IE/IIE primary breast lymphoma

Tumor size

 < 4 cm

-

0.897

 ≥ 4 cm

1.074(0.510–2.258)

0.852

1.060(0.439–2.557)

Nodal sites involved

 Yes

-

-

0.046

 No

0.561(0.272–1.159)

0.118

0.381(0.147–0.983)

Ann arbor stage

 IE

-

-

0.246

 IIE

1.992(0.983–4.322)

0.056

1.661(0.704–4.444)

LDH

 Normal

-

-

0.134

 Elevated

1.719(0.792–3.731)

0.171

1.988(0.809–4.878)

Pathological types

 DLBCL

-

-

0.090

 Non-DLBCL

2.915(1.383–6.134)

0.005

0.463(0.193–1.126)

Local lesion manipulation

 Biopsy

-

-

0.402

 Mastectomy

0.62(0.291–1.333)

0.223

0.676(0.271–1.686)

Radiotherapy

 Yes

-

-

 No

1.685(0.830–3.420)

0.149

2.587(1.083–6.183)

0.032

Chemotherapy

 CHOP

-

-

 E-CHOP

2.008(0.887–4.545)

0.094

1.191(0.397–3.571)

0.754

Rituximab

 Yes

-

-

0.113

 No

4.77(1.666–13.712)

0.004

2.417(0.812–7.189)