Skip to main content

Table 1 Comparison of clinical features between laparoscopic and open surgery groups

From: Safety and feasibility of laparoscopic resection of abdominal neuroblastoma without image-defined risk factors: a single-center experience

Clinical features

Laparoscopic surgery (n = 33)

Open surgery (n = 54)

p

Gender (n, %)

Female

15 (45.45)

28 (51.85)

0.828

Male

18 (54.55)

26 (48.15)

Onset age (months)

 

22 (5, 44)

39 (21, 84)

0.008

Primary site (n, %)

Adrenal

32 (96.97)

35 (64.81)

0.001

Retroperitoneal

1 (3.03)

14 (25.93)

Pelvic

0 (0.00)

5 (9.26)

Maximum diameter of primary tumor (cm)

 

3.06 (1.37)

5.55 (2.77)

0.009

NSE (ng/mL)

 

22.80 (19.70, 34.60)

21.70 (19.00, 29.00)

0.636

LDH (U/L)

 

260.00 (226.00, 303.00)

244.00 (216.50, 295.50)

0.764

INPC (n, %)

Favorable

24 (72.72)

38 (70.37)

0.813

Unfavorable

9 (27.20)

16 (29.63)

MYCN status (n, %)

Not amplified

30 (90.90)

40 (74.07)

0.129

Amplified

2 (6.06)

5 (9.26)

Unknown

1 (3.04)

9 (16.67)

1p (n, %)

Normal

25 (75.75)

39 (72.22)

0.933

Aberration

2 (6.06)

5 (9.26)

Unknown

6 (18.19)

10 (18.52)

11q (n, %)

Normal

24 (72.72)

40 (74.07)

0.962

Aberration

3 (9.09)

4 (7.41)

Unknown

6 (18.19)

10 (18.52)

INRG stage (n, %)

L1

24 (72.73)

54 (100)

 < 0.001

M

4 (12.12)

0

MS

5 (15.15)

0

INRG risk (n, %)

Very low

27 (81.82)

49 (90.74)

0.098

Intermediate

3 (9.09)

0

High

3 (9.09)

5 (9.26)

  1. NSE neuron-specific enolase, LDH lactate dehydrogenase, NB neuroblastoma, GNB ganglioneuroblastoma, GN ganglioneuroma, INPC International Neuroblastoma Pathology Classification System, INRG International Neuroblastoma Risk Group
  2. 1. Continuous variables are presented as the median and interquartile range
  3. 2. Normally distributed variables are presented as mean and standard deviation
  4. 3. Classification variables are presented as numbers (percent)
  5. 4. Reference ranges of tumor markers: serum NSE ≤ 25 ng/mL; serum LDH 110 U/L-295 U/L