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Fig. 7 | World Journal of Surgical Oncology

Fig. 7

From: Hypoxia-induced lncRNA MRVI1-AS1 accelerates hepatocellular carcinoma progression by recruiting RNA-binding protein CELF2 to stabilize SKA1 mRNA

Fig. 7

Hypoxia promotes HCC progression through MRVI1-AS1/SKA1 pathway. A, B Transwell assays were performed by using the indicated MHCC-97H and Hep3B subclones which were incubated in 20% O2 or 1% O2 for 24 h (mean ± SD; n = 3). **P < 0.01, ***P < 0.001, two-way ANOVA. C, D Wound healing assays were performed by using the indicated MHCC-97H and Hep3B subclones which were incubated in 20% O2 or 1% O2 for 24 h (mean ± SD; n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, two-way ANOVA. E, F MTT assays were performed by using the indicated MHCC-97H and Hep3B subclones which were incubated in 20% O2 or 1% O2 (mean ± SD; n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, two-way ANOVA. G, H EdU assays were performed by using the indicated MHCC-97H and Hep3B subclones which were incubated in 20% O2 or 1% O2 for 24 h (mean ± SD; n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, two-way ANOVA

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