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Fig. 5 | World Journal of Surgical Oncology

Fig. 5

From: Hypoxia-induced lncRNA MRVI1-AS1 accelerates hepatocellular carcinoma progression by recruiting RNA-binding protein CELF2 to stabilize SKA1 mRNA

Fig. 5

SKA1 mediates the effects of MRVI1-AS1 on HCC cells metastasis and growth. A, B SKA1 expression in MHCC-97H and Hep3B cells co-transfected with indicated vectors was detected by western blot. C, E Transwell assays revealed that SKA1 mediated the effects of MRVI1-AS1 on migration and invasion of HCC cells (mean ± SD; n = 3). *P < 0.05, two-way ANOVA. D, F Wound healing assays revealed that SKA1 mediated the effect of MRVI1-AS1 on migration of HCC cells (mean ± SD; n = 3). *P < 0.05, two-way ANOVA. G, H MTT assays revealed that SKA1 mediated the effect of MRVI1-AS1 on viability of HCC cells (mean ± SD; n = 3). *P < 0.05, two-way ANOVA. I, J EdU assays revealed that SKA1 mediated the effect of MRVI1-AS1 on proliferation of HCC cells (mean ± SD; n = 3). *P < 0.05, two-way ANOVA

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World Journal of Surgical Oncology

ISSN: 1477-7819

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