Skip to main content

Table 4 The prognostic factors for PFS and OS on univariate and multivariate Cox regression analyses

From: Survival outcomes and the prognostic significance of clinicopathological features in patients with endometrial clear cell carcinoma: a 35-year single-center retrospective study

Variables

PFS

OS

Univariate

Multivariate

Univariate

Multivariate

HR (95%CI)

P value

HR (95% CI)

P value

HR (95%CI)

P value

HR (95% CI)

P value

Age at diagnosis, years

  ≤ 61

Reference

   

Reference

   

  > 61

1.805 (0.946–3.443)

0.073

  

2.985 (1.372–6.491)

0.006

4.297 (1.509–12.238)

0.006

CA125

 Normal

Reference

   

Reference

   

 Elevated

2.357 (1.208–4.599)

0.012

  

2.121 (1.001–4.495)

0.050

  

FIGO Stage

 I/II

Reference

   

Reference

   

 III/IV

5.501 (2.725–11.103)

0.000

5.947 (2.256–15.678)

0.000

3.545 (1.725–7.288)

0.001

3.958 (1.394–11.238)

0.010

Cytoreduction

 Sub-optimal

Reference

   

Reference

   

 Optimal

0.179 (0.042–0.756)

0.019

  

0.502 (0.068–3.694)

0.499

  

Histology

 Mixed

Reference

   

Reference

   

 Pure

1.939 (0.965–3.895)

0.063

  

1.293 (0.63–2.65)

0.483

  

LVSI

 (-)

Reference

   

Reference

   

 ( +)

2.108 (1.094–4.062)

0.026

  

2.12 (1.034–4.346)

0.040

  

MI

  < 1/2

Reference

   

Reference

   

  ≥ 1/2

1.806 (0.954–3.419)

0.069

  

2.409 (1.19–4.878)

0.015

  

PWC

 (-)

Reference

   

Reference

   

 ( +)

5.737 (2.662–12.363)

0.000

3.27 (1.428–7.49)

0.005

2.935 (1.146–7.513)

0.025

  
  1. CI Confidence interval, PFS Progression-free survival, OS Overall survival, CA125 Cancer antigen 125, LVSI Lymphovascular space invasion, MI Myometrial invasion, PWC Peritoneal washing cytology