Variables | PFS | OS | ||||||
---|---|---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | |||||
HR (95%CI) | P value | HR (95% CI) | P value | HR (95%CI) | P value | HR (95% CI) | P value | |
Age at diagnosis, years | ||||||||
  ≤ 61 | Reference |  |  |  | Reference |  |  |  |
  > 61 | 1.805 (0.946–3.443) | 0.073 |  |  | 2.985 (1.372–6.491) | 0.006 | 4.297 (1.509–12.238) | 0.006 |
CA125 | ||||||||
 Normal | Reference |  |  |  | Reference |  |  |  |
 Elevated | 2.357 (1.208–4.599) | 0.012 |  |  | 2.121 (1.001–4.495) | 0.050 |  |  |
FIGO Stage | ||||||||
 I/II | Reference |  |  |  | Reference |  |  |  |
 III/IV | 5.501 (2.725–11.103) | 0.000 | 5.947 (2.256–15.678) | 0.000 | 3.545 (1.725–7.288) | 0.001 | 3.958 (1.394–11.238) | 0.010 |
Cytoreduction | ||||||||
 Sub-optimal | Reference |  |  |  | Reference |  |  |  |
 Optimal | 0.179 (0.042–0.756) | 0.019 |  |  | 0.502 (0.068–3.694) | 0.499 |  |  |
Histology | ||||||||
 Mixed | Reference |  |  |  | Reference |  |  |  |
 Pure | 1.939 (0.965–3.895) | 0.063 |  |  | 1.293 (0.63–2.65) | 0.483 |  |  |
LVSI | ||||||||
 (-) | Reference |  |  |  | Reference |  |  |  |
 ( +) | 2.108 (1.094–4.062) | 0.026 |  |  | 2.12 (1.034–4.346) | 0.040 |  |  |
MI | ||||||||
  < 1/2 | Reference |  |  |  | Reference |  |  |  |
  ≥ 1/2 | 1.806 (0.954–3.419) | 0.069 |  |  | 2.409 (1.19–4.878) | 0.015 |  |  |
PWC | ||||||||
 (-) | Reference |  |  |  | Reference |  |  |  |
 ( +) | 5.737 (2.662–12.363) | 0.000 | 3.27 (1.428–7.49) | 0.005 | 2.935 (1.146–7.513) | 0.025 |  |  |