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Table 1 Demographic and morphological features

From: Survival outcomes and the prognostic significance of clinicopathological features in patients with endometrial clear cell carcinoma: a 35-year single-center retrospective study

Age at diagnosis, median (range), years

61 (31–86)

Menopause

 Yes

80.8% (126/156)

 No

19.2% (30/156)

Medical comorbidities

 Hypertension

36.5% (57/156)

 Diabetes

21.2% (33/156)

 History of Colorectal cancer

5.1% (8/156)

 History of Breast cancer

3.2% (5/156)

CA125, median (range), U/ml

22.1 (5–736.2)

 Elevated

31.9% (46/144)

  Stage I/II

11.1% (16/144)

  Stage III/IV

20.8% (30/144)

 Normal

68.1% (98/144)

FIGO stage

 Stage I

53.2% (83/156)

 Stage II

5.8% (9/156)

 Stage III

29.5% (46/156)

 Stage IV

11.5% (18/156)

Rate of pathology coincidence

 Hysteroscopy

69.6% (32/87)

 Non-hysteroscopy

59.1% (55/87)

Histology, No. (%)

 Pure CCC

59% (92/156)

 Mixed CCC

41% (64/156)

  CCC + EmC

52

  CCC + EmC + carcinosarcoma

1

  CCC + EmC + SC

3

  CCC + SC

8

LVSI

 ( +)

25% (39/156)

MI

  ≥ 1/2

40.6% (63/155)

PWC

 ( +)

14.9% (20/134)

Lymph node metastasis

 No

70.2% (99/141)

 Yes

29.8% (42/141)

  PLN ( +) PALN ( −)

25

  PLN ( −) PALN ( +)

6

  PLN ( +) PALN ( +)

11

Adjuvant treatment

83.3% (130/156)

 CT

81

 RT

5

 CRT

44

No. of postoperative chemotherapy cycles, median (range)

5 (1–9)

  1. CA125 Cancer antigen 125, CCC Clear cell carcinoma, EmC Endometrioid carcinoma, SC Serous carcinoma, LVSI Lymphovascular space invasion, MI Myometrial invasion, PWC Peritoneal washing cytology, CT Chemotherapy, RT Radiation therapy, CRT Chemoradiation, PLN Pelvic lymph nodes, PALN Para-aortic lymph nodes