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Table 1 Baseline characteristics of the analyzed population with IILRR

From: Prognostic factors after isolated ipsilateral local and regional recurrence in HER2-negative luminal breast cancer: a multi-center retrospective study

 

IILRR (n = 80)

Percent (%)

Age (year) at diagnosis

 < 40

17

21.2

 ≥40

63

78.7

Breast operation

 Breast conserving surgery

49

61.2

 Mastectomy

31

38.8

Axilla operation

 No

1

1.2

 SLNB

28

35.0

 ALND

51

63.8

pT

 1

47

58.7

 2

33

41.3

pN

 0

57

71.2

 1

17

21.3

 2

4

5.0

 3

2

2.5

Pathologic stage

 I

68

85.0

 II

10

12.5

 III

2

2.5

ER status

 Negative

2

2.5

 Positive

78

97.5

PR status

 Negative

15

18.7

 Positive

65

81.3

HG

 1

19

23.7

 2

42

52.5

 3

19

23.8

Ki-67

 ≤15%

39

48.7

 > 15

41

51.3

LVI

 No

49

61.2

 Yes

30

37.5

 Unknown

1

1.3

Adjuvant chemotherapy

 No

37

46.3

 Yes

43

53.7

Adjuvant radiotherapy

 No

31

38.8

 Yes

49

61.2

Adjuvant endocrine therapy

 No

5

6.2

 Yes

75

93.8

Site of first recurrence

 Breast

46

57.5

 Axilla

15

18.7

 Chest wall

13

16.3

 Skin

1

1.2

 Breast + axilla

3

3.8

Axilla + chest wall

2

2.5

Number of recurrence

 One

75

93.7

 Two or more

5

6.3

Post-recurrence chemotherapy

 No

45

56.2

 Yes

35

43.8

Post-recurrence radiotherapy

 No

63

78.7

 Yes

17

21.3

Post-recurrence endocrine therapy

 No

34

42.5

 Yes

46

57.5

Progression

 No

46

57.5

 Yes

27

33.7

  Locoregional

4

14.8

  Distant

23

85.2

 Unknown

7

8.8

Death

 No

66

82.5

 Yes

14

17.5

  1. SLNB Sentinel lymph node biopsy, ALND Axillary lymph node dissection, ER Estrogen receptor, PR Progesterone receptor, HG Histologic grade, LVI Lymphovascular invasion