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Table 2 Association of PFKFB3 expression with clinicopathological parameters from breast cancer patients

From: Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation

  

PFKFB3 expression

  
  

(n (%))

P

χ2

Parameter

n

Low

High

  

Age (years)

   

0.618

0.249

 ≤ 50

83

41

42

  

 > 50

77

35

42

  

Blood glucose (mmol/L)

   

< 0.001

25.664

 ≤ 7.0

80

54

26

  

 > 7.0

80

22

58

  

Tumor size (cm)

   

0.501

0.452

 ≤ 2

63

32

31

  

 > 2

97

44

53

  

Lymph node metastasis

   

0.005

8.035

 No

78

46

32

  

 Yes

82

30

52

  

Grade

   

0.954

0.003

 I–II

126

60

66

  

 III

34

16

18

  

Stage

   

< 0.001

38.202

 I–II

92

63

29

  

 III–IV

68

13

55

  
  1. P < 0.05 was considered statistically significant