Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation

Table 1 Expression of PFKFB3 in benign breast tissues and invasive ductal carcinoma (with and without diabetes)

		PFKFB3 expression		P	χ²
Group	n	Low, n (%)	High, n (%)	P	χ²
Benign breast tissues	40	31 (77.5)	9 (22.5)
Invasive ductal carcinoma without diabetes	80	46 (57.5)	34 (42.5)	< 0.001^a	14.731
Invasive ductal carcinoma with diabetes	80	22 (27.5)	58 (72.5)	0.031^b	4.639

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