Fig. 3From: Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activationPFKFB3 promoted proliferation and migration of breast cancer cells in a hyperglycemic environment. BT474-25Â mM and MCF-7-25Â mM cells were transfected with siPFKFB3-1, siPFKFB3-2, or siNC. A The cell counting assay. B MTT assay. C The cell colony formation assay. D The wound-healing assay. E The migration assayBack to article page