World Journal of Surgical Oncology

Table 1 Correlation between CD73 expression and clinical features of patients enrolled

From: Integrative analyses identify CD73 as a prognostic biomarker and immunotherapeutic target in intrahepatic cholangiocarcinoma

Characteristics	FU-iCCA cohort (n = 244)					ZSH cohort (n = 259)
	Patients		CD73 expression			Patients		CD73 expression
	No	%	Low	High	P value	No	%	Low	High	P value
All patients	244	100	140	104		259	100	146	113
Sex
Female	106	43.4	62	44	0.758	99	38.2	67	32	0.004
Male	138	56.6	78	60		160	61.8	79	81
Age
≤ 60	113	46.3	67	46	0.574	125	48.3	69	56	0.714
> 60	131	53.7	73	58		134	51.7	77	57
HBsAg
Negative	179	73.4	104	75	0.705	179	69.1	97	82	0.290
Positive	65	26.6	36	29		80	30.9	49	31
Liver cirrhosis
No	222	91.0	128	94	0.778	186	71.8	104	82	0.813
Yes	22	9.0	12	10		73	28.2	42	31
Vascular invasion
No	141	57.8	87	54	0.110	185	71.4	115	70	0.003
Yes	103	42.2	53	50		74	28.6	31	43
LN metastasis
No	194	79.5	114	80	0.389	207	79.9	124	83	0.022
Yes	50	20.5	26	24		52	20.1	22	30
Tumor size
≤ 5 cm	108	44.3	63	45	0.788	116	44.8	71	45	0.158
> 5 cm	136	55.7	77	59		143	55.2	75	68
CA199
≤ 37 U/mL	109	44.7	75	34	0.001	116	44.8	76	40	0.008
> 37 U/mL	135	55.3	65	70		143	55.2	70	73
CEA
≤ 5 ng/mL	185	75.8	116	69	0.003	189	73.0	118	71	0.001
> 5 ng/mL	59	24.2	24	35		70	27.0	28	42
AJCC 8th
I–II	154	63.1	96	58	0.040	203	78.4	122	81	0.021
III–IV	90	36.9	44	46		56	21.6	24	32

Data in bold indicated statistical significance
ZSH cohort Zhongshan Hospital cohort, LN Lymph node, CEA Carcinoembryonic antigen, AJCC American Joint Committee on Cancer

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