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Fig. 6 | World Journal of Surgical Oncology

Fig. 6

From: Integrative analyses identify CD73 as a prognostic biomarker and immunotherapeutic target in intrahepatic cholangiocarcinoma

Fig. 6

Correlation analysis of CD73 expression and immune checkpoints in ICC. A Correlation between CD73 expression and immune checkpoint levels. B Correlation between CD73 expression and CD44 mRNA level. C Immune checkpoint levels in the CD73 high mRNA group compared with the CD73 low mRNA group in the FU-iCCA cohort. D Representative images showing negative to strong expression of HHLA2 detected by IHC. E Kaplan–Meier survival curves for OS according to HHLA2 expression level in the FU-iCCA cohort. F HHLA2 expression levels in the CD73 high group compared with the CD73 low group in the ZSH cohort. IHC, immunohistochemistry; MOD, mean optic density. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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World Journal of Surgical Oncology

ISSN: 1477-7819

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