Table 1 Overview of collected studies
Reference | Study design | Approach | Patients(n) | Comparability | Clinical stage | Tumor pathology | Quality score | Level of evidence | Follow-up (month) |
|---|---|---|---|---|---|---|---|---|---|
Yin (2021) [24] | Retrospective | RLRN | 58 | 1, 2, 3, 4, 5 | All is T2 and T3 | Clear cell: 47. Papillary: 7. Chromophobe: 3. Collecting duct: 1 | 6 b | 4 | 23.3 ± 4.4 |
TLRN | 58 | Clear cell: 51. Papillary: 10. Chromophobe:7 | |||||||
Chu (2019) [15] | RCT | RLRN | 36 | 1, 2, 3, 4, 5, 7 | All is T2 and T3 | NA | 5 a | 2b | NA |
TLRN | 36 | ||||||||
Huang (2018) [13] | RCT | RLRN | 40 | 1, 2, 3, 4, 5, 7 | NA | NA | 5 a | 2b | NA |
TLRN | 40 | ||||||||
Chen (2018) [14] | RCT | RLRN | 32 | 1, 2 | NA | NA | 4 a | 2b | NA |
TLRN | 32 | ||||||||
Zhang (2017) [22] | Retrospective | RLRN | 53 | 1, 2, 3, 4, 5 | All is T2 and T3 | NA | 5 b | 4 | NA |
TLRN | 52 | ||||||||
Kim (2017) [23] | Retrospective | TLRN | 30 | 1, 2, 3, 4, 5 | T2:18 T3:6 T4:6 | Clear cell: 26. Other: 4 | 6 b | 4 | NA |
RLRN | 34 | T2:17 T3:10 T4:7 | Clear cell: 31. Other:3 | ||||||
Wu (2016) [21] | Retrospective | TLRN | 30 | 1, 2, 3, 4, 5, 6, 7 | All is T2 and T3 | NA | 5 b | 4 | NA |
RLRN | 30 | ||||||||
Song (2016) [20] | Retrospective | RLRN | 43 | 1, 2 | All is T2 and T3 | NA | 5 b | 4 | NA |
TLRN | 43 | ||||||||
Chen (2016) [19] | Retrospective | TLRN | 35 | 1, 2, 3, 4, 5, 6, 7 | T2:15 T3:20 | NA | 5 b | 4 | 6 |
RLRN | 38 | T2:32 T3:6 | |||||||
Qin (2015) [12] | RCT | TLRN | 50 | 1, 2, 4, 5 | NA | NA | 4 a | 2b | NA |
RLRN | 50 | ||||||||
Huang (2015) [11] | RCT | TLRN | 40 | 1, 2, 4, 5 | T2:15 T3:25 | NA | 5 a | 2b | NA |
RLRN | 40 | T2:26 T3:14 | |||||||
Xu (2014) [18] | Retrospective | RLRN | 42 | 1, 2, 3, 4, 5 | T2:35 T3:7 | Clear cell:42 | 5 b | 4 | NA |
TLRN | 26 | T2:21 T3:5 | Clear cell: 26 | ||||||
Yang (2013) [17] | Retrospective | TLRN | 23 | 1, 2, 3, 4, 5, 6, 7 | T2:10 T3:13 | Clear cell: 23 | 6 b | 4 | NA |
RLRN | 37 | T2:28 T3:9 | Clear cell: 31. Papillary: 2. Chromophobe: 2. Collecting duct: 1. Eosinophilic: 1 | ||||||
Steinberg (2004) [16] | Retrospective | RLRN | 40 | 2, 3, 5 | All is T2, T3 and T4 | NA | 5 b | 4 | NA |
TLRN | 25 |