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Table 2 Unadjusted and multivariate adjusted model for association of duodenal invasion with adverse features of pancreatic cancer

From: The prognostic significance of duodenal wall invasion in pancreatic adenocarcinoma

Adverse features of pancreatic cancer

Duodenal invasion, OR (P-value)

Univariate model

Multivariate modela

Age

1.97 (P = 0.14)

3.53 (P = 0.07)

Gender

1.49 (P = 0.33)

1.81 (P = 0.34)

Race

0.70 (P = 0.61)

1.09 (P = 0.88)

Lymphovascular invasion

2.71 (P = 0.03)*

0.83 (P = 0.84)

Lymph node involvement

3.89 (P = 0.004)*

9.17 (P = 0.02)*

Perineural involvement

2.82 (P = 0.07)

1.04 (P = 0.96)

CBD involvement

1.38 (P = 0.54)

0.34 (P = 0.16)

IPMN-associated adenocarcinoma

0.68 (P = 0.50)

0.18 (P = 0.06)

T stage

 T2 vs T1

1.96 (P = 0.21)

0.29 (P = 0.15)

 T3 vs T1

2.50 (P = 0.14)

0.98 (P = 0.98)

Grade

 G2 vs G1

4.65 (P = 0.18)

2.09 (P = 0.62)

 G3 vs G1

7.11 (P = 0.10)

4.61 (P = 0.32)

Margin status

0.69 (P = 0.41)

0.86 (P = 0.81)

Recurrence

0.98 (P = 0.96)

1.30 (P = 0.66)

Mortality

0.43 (P = 0.054)

0.13 (P = 0.03)*

  1. aAll models are adjusted for other variables listed
  2. *P-value significant at ≤ 0.05
  3. Missing values—neoadjuvant treatment (12), race (9)