Table 1 Biochemical remission rate of somatotroph tumors after endoscopic transsphenoidal surgery (investigator’s definition as criteria)
Study or subgroup | Biochemical remission (n) | Total (n) | Rate | Definition of remission |
|---|---|---|---|---|
M. S. Kabil, 2005 | 41 | 48 | 0.854 | N/A |
A. Rudnik, 2005 | 10 | 12 | 0.833 | N/A |
W. M. Lui, 2001 | 5 | 5 | 0.917 | GH ≤ 2 μg/l |
Christa C. van Bunderen, 2013 | 9 | 30 | 0.3 | Normal IGF-1, |
No active clinical symptoms | ||||
Abtin Tabaee, 2009 | 5 | 6 | 0.833 | N/A |
Guan Sun, 2017 | 6 | 7 | 0.857 | Normal GH |
Alexander P. Kelly, 2022 | 1 | 2 | 0.5 | Normal IGF-I |
Chao Tao, 2021 | 10 | 13 | 0.769 | 2010 |
Heping Zhou, 2017 | 67 | 86 | 0.779 | N/A |
Shigetoshi Yano, 2017 | 26 | 47 | 0.553 | Inconsistent |
J. Lenzi, 2015 | 15 | 22 | 0.682 | N/A |
Fuyu Wang, 2015 | 119 | 180 | 0.661 | N/A |
Carlos Takahiro Chone, 2014 | 6 | 7 | 0.857 | N/A |
P. Cappabianca, 1999 | 4 | 5 | 0.8 | N/A |
A. Gamea, 1994 | 4 | 5 | 0.8 | GH 5 ≤ ng/ml |
Andreja Maric, 2012 | 15 | 21 | 0.714 | IGF-1 < 420 ng/mL and GH < 5.0 ng/mL |