Table 4 Logistic regression analysis for risk factors associated with neutropenia before first postoperative chemotherapy
Univariable OR (95% CI) | p | Multivariable OR (95% CI) | p | |
|---|---|---|---|---|
Sarcopenia | 4.23 (1.41, 12.66) | 0.01* | 5.58 (1.70, 18.29) | 0.005* |
Gender | ||||
Female | 1 | |||
Male | 0.89 (0.31, 2.57) | 0.83 | ||
Age (years) | 0.99 (0.95, 1.03) | 0.45 | ||
BMI (kg/m2) | 0.98 (0.83, 1.16) | 0.82 | ||
Comorbidity | 0.72 (0.25, 2.13) | 0.56 | ||
Tumor initial location | ||||
Stomach | 1 | |||
Colorectum | 0.74 (0.24, 2.29) | 0.60 | ||
Preoperative chemotherapy | 2.14 (0.65, 7.04) | 0.21 | ||
Preoperative tests results | ||||
Albumin (g/l) | 0.84 (0.72, 0.97) | 0.015* | 0.81 (0.69, 0.95) | 0.008* |
WBC (× 109/l) | 0.90 (0.67, 1.21) | 0.48 | ||
Neutrophil (× 109/l) | 0.77 (0.51, 1.16) | 0.21 | ||
Type of HIPEC | ||||
Prophylactic | 1 | |||
Therapeutic | 0.70 (0.23, 2.18) | 0.54 | ||
Session of HIPEC | ||||
One | 1 | |||
Two | 0.67 (0.11, 4.15) | 0.66 | ||
Three | 1.44 (0.28, 7.47) | 0.66 | ||