Table 3 Logistic regression analysis for risk factors associated with leukopenia before first postoperative chemotherapy
Univariable OR (95% CI) | p | Multivariable OR (95% CI) | p | |
|---|---|---|---|---|
Sarcopenia | 2.35 (0.85, 6.44) | 0.098 | 2.76 (0.96, 7.96) | 0.06 |
Gender | ||||
Female | 1 | |||
Male | 1.11 (0.40, 3.11) | 0.84 | ||
Age (years) | 1.00 (0.96, 1.04) | 0.88 | ||
BMI (kg/m2) | 1.02 (0.88, 1.19) | 0.79 | ||
Comorbidity | 0.59 (0.20, 1.69) | 0.32 | ||
Tumor initial location | ||||
Stomach | 1 | |||
Colorectum | 0.43 (0.13, 1.42) | 0.17 | ||
Preoperative chemotherapy | 1.2 (0.36, 4.22) | 0.75 | ||
Preoperative test results | ||||
Albumin (g/l) | 0.86 (0.75, 0.98) | 0.027* | 0.85 (0.73, 0.97) | 0.018* |
WBC (× 109/l) | 0.82 (0.61, 1.11) | 0.20 | ||
Neutrophil (× 109/l) | 0.81 (0.55, 1.18) | 0.26 | ||
Type of HIPEC | ||||
Prophylactic | 1 | |||
Therapeutic | 1.1 (0.37, 2.95) | 0.93 | ||
Session of HIPEC | ||||
One | 1 | |||
Two | 1.47 (0.34, 6.42) | 0.61 | ||
Three | 1.14 (0.38, 3.40) | 0.81 | ||