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Table 4 Multivariable logistic regression analyses of association between possible predictive factors and the presence of most severe complication (CDC ≥ 3b)

From: Reporting perioperative complications of radical cystectomy: the influence of using standard methodology based on ICARUS and EAU quality criteria

 

30 days

90 days

 

Univariable

Multivariable

Univariable

Multivariable

 

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

Age

0.345

1.02 (0.98–1.07)

  

0.183

1.03 (0.99–1.08)

  

BMI ≥ 25 kg/m2

0.019

2.51 (1.16–5.43)

0.020

2.66 (1.17–6.05)

0.003

3.06 (1.47–6.36)

0.002

3.62 (1.58–8.29)

Preoperative Hb

0.779

0.97 (0.79–1.19)

  

0.333

0.91 (0.75–1.10)

  

Preoperative albumin

0.910

0.97 (0.54–1.74)

  

0.742

0.91 (0.53–1.57)

  

Albumin/total protein

0.967

1.07 (0.04–30.15)

  

0.982

0.97 (0.04–22.27)

  

e-GFR

0.039

0.99 (0.97–1.00)

0.408

0.99 (0.97–1.01)

0.003

0.98 (0.97–0.99)

0.296

0.99 (0.97–1.00)

Presence of hydronephrosis

0.173

0.58 (0.27–1.26)

  

0.324

0.69 (0.33–1.44)

  

Prior abdominal surgery

0.756

0.88 (0.38–2.03)

  

0.934

0.97 (0.44–2.15)

  

Prior systemic chemotherapy

0.136

0.52 (0.22–1.23)

  

0.025

0.40 (0.18–0.89)

0.026

0.34 (0.13–0.88)

Operation time

0.778

1.00 (0.99–1.01)

  

0.492

0.99 (0.99–1.00)

  

ACCI

< 0.001

1.56 (1.22–1.98)

0.002

1.49 (1.15–1.91)

< 0.001

1.55 (1.24–1.93)

0.003

1.49 (1.14–1.94)

SIRI

0.012

1.21 (1.04–1.41)

0.347

1.09 (0.90–1.34)

< 0.001

1.32 (1.14–1.55)

0.031

1.27 (1.02–1.57)

PNI

0.910

0.10 (0.94–1.06)

  

0.687

0.99 (0.94–1.04)

  

AGR

0.924

1.02 (0.73–1.41)

  

0.827

0.97 (0.70–1.33)

  

PLR

0.039

1.01 (1.00–1.01)

0.189

1.00 (0.99–1.01)

0.020

1.01 (1.00–1.01)

0.392

1.00 (0.99–1.01)

  1. Abbreviations: CDC Clavien-Dindo classification, BMI body mass index, e-GFR estimated glomerular filtration rate, SIRI systemic inflammatory response index, PNI prognostic nutritional index, AGR albumin-to-globulin ratio, PLR platelet-to-lymphocyte ratio
  2. The bold p-values indicate a p < 0.05, which is a statistically significant difference