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Table 1 Baseline characteristics of enrolled patients with HCC

From: Efficacy of treatment based on TKIs in combination with PD-1 inhibitors for unresectable recurrent hepatocellular carcinoma

Variable

Value, n=44 (%)

Age (year)

57 ± 8.9

Sex male/female

40 (90.9%)/4 (9.1%)

BMI

25.0 ± 3.3

Drinking no/yes

15 (34.1%)/29 (65.9%)

HBsAg negative/positive

7 (15.9%)/37 (84.1%)

HCV negative/positive

39 (88.6%)/5 (11.4%)

Time interval from radical (hepatectomy to advanced recurrence) ≤ 1 year/> 1 year

24 (54.5%)/20 (45.5%)

Liver cirrhosis no/yes

10 (22.7%)/34 (77.3%)

Number of intrahepatic lesions ≤ 3/>3

21 (47.7%)/23 (52.3%)

PVTT classification

 No portal vein tumor thrombosis

37 (84.1%)

 VP2

1 (2.3%)

 VP3

4 (9.1%)

 VP4

2 (4.5%)

Extrahepatic metastases

 No

21 (47.7%)

 Yes

23 (52.3%)

  Bone metastases

5 (11.4%)

  Lung metastases

7 (15.9%)

  Lymph node metastases

3 (6.8%)

  Abdominal metastases

5 (11.4%)

  Diaphragmatic metastases

3 (6.8%)

BCLC staging at recurrence B/C

15 (34.1%)/29 (65.9%)

Ascites no/yes

42 (95.5%)/2 (4.5%)

AFP (≤ 400 ng/mL)

38 (86.4%)

Child-Pugh classification A/B

40 (90.9%)/4 (9.1%)

ECOG performance 0/1

35 (79.5%)/9 (20.5%)

ALT (U/L)

32.1 ± 23.6

AST (U/L)

36.6 ± 23.1

ALB (g/L)

41.0 ± 5.8

Total bilirubin level (mg/dL)

15.0 ± 6.9

  1. BMI body mass index, HBsAg hepatitis B surface antigen, HCV hepatitis C virus, PVTT portal vein tumour thrombosis, BCLC Barcelona Clinic Liver Cancer Group, AFP alpha-fetoprotein, ECOG Eastern Cooperative Oncology Group, ALT alanine aminotransferase, AST aspartate aminotransferase, ALB albumin