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Table 1 IMTs in the CBD have been previously reported cases in addition to present case

From: Inflammatory myofibroblastic tumour of the common bile duct: a case report and literature review

Authors/publication year

Age/sex

Symptoms

Tumour marker

Liver function test

Location

Size (cm)

Immunohistochemistry

Treatment

Follow-up/outcome

E. E. Haith et al. [6] (1964)

6/M

Jaundice

Distal CBD

EHBD excision

5 months/NR

J. D. Stamatakis et al. [11] (1979)

13/F

Jaundice, abdominal pain

 

TB: 13.4 mg/dL

CBD, CD, CHD

3 cm × 3 cm

PD & celecoxib

21 months/NR

H. Ikeda et al. [12] (1990)

43/F

Fever, jaundice, significant weight loss

CHD, ProxCBD

Surgery

7 months/lung mets.

N. Fukushima et al. [13] (1997)

58/F

Abnormal liver function on physical examination

Normal

TB: 0.7 mg/dl, AST: 159 U/l, ALT: 454 U/l

Mid-lower CBD

2 cm × 2 cm

Vimentin (+), desmin (−), muscle-specific actin (−) and CD34 (+)

PD surgery

Not mentioned

S. V. Walsh et al. [14] (1998)

50/M

Proximal CBD

PD

19 years/metastasis

R. Sobesky et al. [15] (2003)

51/F

Jaundice

Normal

TB: 20.8mg/dL

Distal CBD

1.5 cm

CD34 (+), desmin (+), S-100 (+), SMA+

PD

2 years/NR

Antonio Martín Malagón et al. [16] (2006)

51/F

Jaundice

Normal

TB/DB: 11.3/9.3 mg/dl

Distal CBD

0.7 cm × 0.7 cm

SMA (+), S100 (−), vimentin (+), CD45 (+), CD68 (+)

PD

1 year/NR

Anuradha Sekaran et al. [17] (2006)

17/F

Jaundice, abdominal pain, black stool

TB/DB: 3.9/2.3 mg/dL

Distal CBD

SMA (+), S100 (+), vimentin (+)

PD

6 weeks/NR

E M López-Tomassetti

Fernández et al. [18] (2006)

55/F

Jaundice

Distal CBD

5 cm × 5 cm

Cortical steroid therapy

3 months/tumor regression

Bassam Abu-Wasel et al. [19] (2012)

55/M

Jaundice

Normal

TB: 20.8mg/dL

Distal CBD

3 cm × 3 cm

PD

14 months/NR

K. Vasiliadis et al. [20] (2013)

70/F

Jaundice

Normal

DB: 14.9 mg/dl

Mid-distal CBD

3 cm × 3 cm

PD

8 months/NR

Aureen D’Cunha et al. [21] (2016)

12/F

Jaundice, abdominal pain

TB/DB: 13.86 /12.1 mg/dL

Distal CBD

4 cm × 4 cm

SMA (+), ALK (+)

PD

9 months/NR

Ritu Verma et al. [3] (2019)

24/F

Jaundice

Normal

TB/DB: 5.8/2.9 mg/dL

Mid CBD

10 cm × 6 cm

Desmin (+), SMA+, (CK), CD34 (−), CD117 (−), DOG1 (−), ALK1 (−)

PD

Not mentioned

Present case

34/M

Jaundice

CA199: 58.5 U/ml

TB/DB: 5.17/2.49 mg/dL

Mid CBD

2 cm × 2 cm

Vimentin (+), ALK (+), SMA (+), desmin (−), CK7 (−), S-100 (−), CD34 (−), DOG1 (−), CD117 (−), Ki-67 (20%+)

PD

3 years/NR

  1. M male, F female, CBD common bile duct, PD pancreatoduodenectomy, CD cystic duct, CHD common hepatic duct, EHBD extrahepatic bile duct, TB total bilirubin, DB direct bilirubin, NR no recurrence