Fig. 5From: Differential treatment responses to immune checkpoint inhibitor (ICI) therapy in a case of multiple primary malignancies: the programmed death ligand-1 (PD-L1) negative ureteral and lung metastasis from a clear cell renal cell carcinoma appearing after robotic-assisted partial nephrectomy progressed after ICI therapy, while synchronous PD-L1-positive primary lung squamous cell carcinoma responded very well to ICI therapy: a case reportProgrammed death-ligand 1 (PD-L1 clone 22C3) immunohistochemistry in A lung SCC, B the renal tumor, C ureteral metastasis, and D lung metastasis from the RCC. The tumor proportion score (TPS) in B, C, and D was < 1%, whereas that in A was 1–49%. PD-L1, reduced from 100 × Back to article page