Risk assessment of cytologically indeterminate thyroid nodules with integrated molecular testing and repeat biopsy: a surgical decision-oriented tool

Table 4 Performance of the risk assessment tool for cytologically indeterminate samples. Performance of repeat aspiration when no molecular alterations detected on AUS/FLUS and FN/SFN (N = 13)

Risk assessment	Malignant reference standard	Benign reference standard
High risk	6	0
Low risk	1	6

Sensitivity, 85.7%; specificity, 100%; PPV, 100%; NPV, 85.7%; AUC, 0.929; p < 0.05
Abbreviations: AUS/FLUS atypia (or follicular lesions) of undetermined significance, FN/SFN follicular neoplasms or lesions suspicious for follicular neoplasm, SUSP suspicious of malignancy, NPV negative predictive value, PPV positive predictive value, AUC the area under receiver operating characteristic curve

ISSN: 1477-7819