Risk assessment of cytologically indeterminate thyroid nodules with integrated molecular testing and repeat biopsy: a surgical decision-oriented tool

Table 3 Performance of the risk assessment tool for cytologically indeterminate samples. Performance of integrated risk assessment on AUS/FLUS and FN/SFN (N = 55)

Risk assessment	Malignant reference standard	Benign reference standard
High risk	28	1
Low risk	11	15

Sensitivity, 71.8%; specificity, 93.8%; PPV, 96.6%; NPV, 57.7%; AUC, 0.828; p < 0.05
Abbreviations: AUS/FLUS atypia (or follicular lesions) of undetermined significance, FN/SFN follicular neoplasms or lesions suspicious for follicular neoplasm, SUSP suspicious of malignancy, NPV negative predictive value, PPV positive predictive value, AUC the area under receiver operating characteristic curve

ISSN: 1477-7819