Risk assessment of cytologically indeterminate thyroid nodules with integrated molecular testing and repeat biopsy: a surgical decision-oriented tool

Table 1 Performance of the risk assessment tool for cytologically indeterminate samples. Performance on cytologically indeterminate thyroid nodules (N = 87)

Risk assessment	Malignant reference standard	Benign reference standard
High risk	58	3
Low risk	11	15

Sensitivity, 84.1%; specificity, 83.3%; PPV, 95.1%; NPV, 57.7%; AUC, 0.837; p < 0.05
Abbreviations: AUS/FLUS atypia (or follicular lesions) of undetermined significance, FN/SFN follicular neoplasms or lesions suspicious for follicular neoplasm, SUSP suspicious of malignancy, NPV negative predictive value, PPV positive predictive value, AUC the area under receiver operating characteristic curve

ISSN: 1477-7819