Table 1 Clinicopathological characteristics of patients with parathyroid carcinoma
Characteristic | Number/median | %/[IQR] |
|---|---|---|
No. of patients | 38 | |
Age, year | 56.5 | [46.0, 67.5] |
Sex | ||
Male | 11 | 28.9% |
Female | 27 | 71.1% |
Preoperative calcium (mg/dl) | 11.5 | [10.9, 12.8] |
Preoperative intact PTH (pg/ml) | 252 | [163.5, 370.6] |
Tumor size, mm | 29 | [17, 35.5] |
Surgical procedure | ||
Parathyroidectomy only | 17 | 44.7% |
Parathyroidectomy + thyroid lobectomy | 8 | 21.0% |
Parathyroidectomy + thyroid lobectomy + lymph node dissection | 13 | 34.3% |
Postoperative radiotherapy | ||
Yes | 2 | 5.2% |
No | 36 | 94.8% |
Histological component cells | ||
Chief cells | 31 | 81.6% |
Oxyphil cells | 7 | 18.4% |
Capsular invasion | ||
Yes | 35 | 92.1% |
No | 3 | 7.9% |
Vascular invasion | ||
Yes | 21 | 55.3% |
No | 17 | 44.7% |
Histological necrosis | ||
Yes | 5 | 13.2% |
No | 33 | 86.8% |
Lymph node metastasis | ||
Yes | 1 | 2.6% |
No | 12 | 31.6% |
Not dissecting | 25 | 65.8% |
Weight of tumor (mg) | 3930 | [1180, 8070] |
Ki-67 index (%) | 0.875 | [0.35, 1.75] |
Postoperative course | ||
Local recurrence + distant metastasis | 1 | 2.6% |
Distant metastasis | 3 | 7.9% |
Ongoing hypercalcemia | 1 | 2.6% |
Tumor-specific death | ||
Yes | 3 | 7.9% |
No | 35 | 92.1% |
Follow-up time (months) | 63.7 | [31.6, 127.9] |