Fig. 4
METTL3 enhances the stability of lncRNA METTL4-2 transcript and upregulates its expression. A The SRAMP tool was used to screen m6A modification sites of METTL4-2. B The enrichment of METTL4-2 followed by MeRIP-qRT-PCR assay in C33A cells (n=3). C m6A modification in C33A cells was conducted by colorimetric quantificational analysis (n=3). D The effect of METTL3 silencing on METTL4-2 expression was detected by qRT-PCR (n=3). E MeRIP‐qPCR demonstrated the m6A modification of METTL4-2 in C33A cells with METTL3 knockdown transfection (n=3). *p<0.05, **p<0.01, ***p<0.001