Fig. 2

Abnormal expression of METTL3 affects the progression of CSCC. A METTL3 expression was examined using qRT-PCR in C33A cells transfected with sh-NC, Sh-METTL3#1, Sh-METTL3#2, and METTL3 OE (n=3). B The proliferation of C33A cells was detected with a CCK-8 kit (n=3). C Colony formation assays (n=3). Cell migration and invasion were detected by D transwell assay and E wound healing assay (n=3). F The levels of E-cadherin, N-cadherin, vimentin, and FN1 in C33A cells were detected by western blot (n=3). **p < 0.01; ***p < 0.001