Fig. 1
METTL3 is upregulated in CSCC tissues and cells. A Expression levels of m6A writers (METTL3, METTL14, and WTAP) and erasers (FTO and ALKBH5) were detected in the TCGA database. B qRT-PCR detected METTL3 expression in CSCC tissues and normal tissues (n=8). C The protein expression of METTL3 was detected by western blot in CSCC metastatic tissues (T) and non-metastatic tissues (N) (n=3). D Immunohistochemistry (IHC) staining was used to reveal METTL3 protein expression in CSCC tissues (n=3). E The mRNA level of METTL3 in CSCC cell lines (SiHa and C33A) and normal cervical epithelial cells (H8) was detected by qRT-PCR (n=3). F METTL3 expression in CSCC metastatic tissues and non-metastatic tissues was detected by qRT-PCR and G western blot (n=3). **p < 0.01; ***p < 0.001