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Table 4 Upstaging risk factor analysis for ductal carcinoma in situ diagnosed using mammography (MG)-guided procedures (N = 72)

From: High rate of postoperative upstaging of ductal carcinoma in situ when prioritizing ultrasound evaluation of mammography-detected lesions: a single-center retrospective cohort study

Variables

Overall

DCIS

(n = 67)

Invasive cancer (%)

(n = 5)

Pa

MG-associated factors

 BI-RADS category

72

  

0.72

  3

 

1

0

 

  4

 

9

0

 

  4a

 

16

1 (5.9)

 

  4b

 

28

4 (12)

 

  4c

 

11

0

 

  5

 

2

0

 

 Breast density

72

  

>0.99

  B

 

1

0

 

  C

 

63

5

 

  D

 

3

0

 

 Mass or distortion

67

  

0.43

  No

 

56

4 (6.7)

 

  Yes

 

6

1 (14)

 

 MG calcification

67

  

>0.99

  No

 

2

0

 

  Yes

 

61

4 (6.2)

 

Biopsy DCIS factors

 Diagnostic method

72

  

0.65

  ST-VAB

 

28

3 (9.7)

 

  WLSB

 

39

2 (4.9)

 

 DCIS grade

61

  

>0.99

  Low

 

13

1

 

  Intermediate

 

27

1

 

  High

 

18

1

 

 Suspicion of microinvasion

71

  

(NA)

  No

 

66

5 (7.0)

 

  Yes

 

0

0

 

 ER

57

  

>0.99

  Negative

 

6

0

 

  Positive

 

46

5 (9.8)

 
  1. Abbreviations: BI-RADS The Breast Imaging Reporting and Data System, US-CNB ultrasound-guided core needle biopsy, ST-VAB stereotactic vacuum-assisted breast biopsy, WLSB wire-localized surgical biopsy, US ultrasound, MG mammogram, DCIS ductal carcinoma in situ, ER estrogen receptor
  2. aFisher’s exact test