Skip to main content

Table 3 Upstaging risk factor analysis for US-CNB-diagnosed DCIS (N = 200)

From: High rate of postoperative upstaging of ductal carcinoma in situ when prioritizing ultrasound evaluation of mammography-detected lesions: a single-center retrospective cohort study

Variables

 

Logistic regression

Multiple logistic regression

n

OR

95% CI

P

OR

95% CI

P

US variables

 Palpability

200

3.0

1.6–5.7

<0.001

2.3

0.9–6.2

0.1

 Lesion size (cm)

185

2.1

1.4–3.3

<0.001

1.73

0.98–3.4

0.08

 BI-RADS category (5)

176

3.6

0.97–23.3

0.10

   

 US-detected calcification

170

1.6

0.7–4.3

0.30

   

Associated MG variables

 BI-RADS category (0, 4, 5)

157

1.5

0.7–3.2

0.30

   

 Mass or distortion

141

0.98

0.5–2.0

0.95

   

 Calcification

143

2.2

1.04–4.6

0.04

1.6

0.6–4.2

0.3

Biopsy DCIS pathologic variables

 Core biopsy strip number

181

1.2

0.95–1.5

0.16

   

 High DCIS grade

145

4.8

2.2–11.6

<0.001

2.6

0.98–7.5

0.06

 Suspicious for microinvasion

190

7.1

1.4–129

0.06

4.0

0.6–77

0.2

 Negative ER

160

1.34

0.6–3.0

0.45

   
  1. Abbreviations: OR odds ratio, CI confidence interval, BI-RADS The Breast Imaging Reporting and Data System, CNB core needle biopsy, DCIS ductal carcinoma in situ, ER estrogen receptor