Variable | DFS | OS | ||
---|---|---|---|---|
HR (95%CI) | P value | HR (95%CI) | P value | |
Age | Â | Â | Â | Â |
 ≤ 60 | 1 |  | 1 |  |
 60 | 1.25(0.88–1.53) | 0.147 | 1.19(0.84–1.71) | 0.212 |
Sex | Â | Â | Â | Â |
 Male | 1 |  | 1 |  |
 Female | 1.05(0.79–1.19) | 0.412 | 0.93(0.56–1.27) | 0.670 |
BMI (kg/m2) | Â | Â | Â | Â |
 22.78 | 1 |  | 1 |  |
 ≤ 22.78 | 0.96(0.67–1.37) | 0.198 | 1.17(0.91–1.43) | 0.219 |
Tumor size(cm) | Â | Â | Â | Â |
 ≤ 10 | 1 |  | 1 |  |
 10 | 4.04(2.67–6.79) |  < 0.001 | 3.74(2.42–5.43) | 0.003 |
Tumor site | Â | Â | Â | Â |
 Stomach | 1 |  | 1 |  |
 DU + SM | 1.71(1.45–2.43) | 0.009 | 1.48(1.16–1.89) | 0.017 |
 Others | 2.49(1.35–4.34) |  < 0.001 | 1.77(1.59–2.18) |  < 0.001 |
Histological variant | Â | Â | Â | Â |
 Spindle | 1 |  | 1 |  |
 Epithelioid | 0.87(0.74–1.40) | 0.122 | 0.69(0.54–1.27) | 0.208 |
 Mixed | 1.08(1.01–1.33) | 0.028 | 0.97(0.95–1.09) | 0.091 |
Surgery | Â | Â | Â | Â |
 Local excision | 1 |  | 1 |  |
 Contained DTE | 1.26(0.89–1.73) | 0.011 | 1.11(1.09–1.24) | 0.032 |
 Extensive radical surgery | 1.86(0.91–2.42) |  < 0.001 | 2.47(1.71–3.39) |  < 0.001 |
Ki-67 index(%) | Â | Â | Â | Â |
 ≤ 10 | 1 |  | 1 |  |
 10 | 3.14(2.40–4.67) |  < 0.001 | 2.43(1.96–3.51) |  < 0.001 |
Mitotic rate | Â | Â | Â | Â |
 ≤ 10/50 | 1 |  | 1 |  |
 10/50 | 2.79(2.16–4.08) |  < 0.001 | 2.13(1.76–3.09) |  < 0.001 |
TKI therapy | Â | Â | Â | Â |
 Regular | 1 |  | 1 |  |
 Irregular + no drug | 3.11(2.08–4.55) |  < 0.001 | 2.47(1.84–3.91) |  < 0.001 |