Factors | N | △PSQI (6-month postoperative-preoperative) | ||
---|---|---|---|---|
Group A (n = 38) | Group B (n = 11) | P-value | ||
Patient-related factors | ||||
Sex, M/F | 31/18 | 22/16 | 9/2 | 0.274 |
Age, ≤ 60 years/ > 60 years | 27/22 | 24/14 | 3/8 | 0.078 |
BMI, ≤ 24 kg/m2/ > 24 kg/m2 | 29/20 | 22/16 | 7/4 | > 0.999 |
Smoking within 2 h of bedtime, no/yes | 24/25 | 19/19 | 5/6 | 0.791 |
Alcohol within 2 h of bedtime, no/yes | 38/11 | 31/7 | 7/4 | 0.398 |
Duration of symptoms, ≤ 2 m/ > 2 m | 22/27 | 16/22 | 6/5 | 0.699 |
Pain worsening at night, no/yes | 18/31 | 10/28 | 8/3 | 0.014 |
Decrease in VAS, ≤ 3/ > 3 | 29/20 | 19/19 | 10/1 | 0.037 |
Increase in Frankel Grade, ≤ 2/ > 2 | 39/10 | 30/8 | 9/2 | > 0.999 |
Increase in ECOG-PS, ≤ 2/ > 2 | 35/14 | 24/14 | 11/0 | 0.045 |
Comorbidity, no/yes | 27/22 | 20/18 | 7/4 | 0.763 |
Tumor-related factors | ||||
Tumor size, < 3 cm/ ≥ 3 cm | 9/40 | 8/30 | 1/10 | 0.645 |
Tumor site, cervical/not cervical | 15/34 | 11/27 | 4/7 | 0.921 |
Tumor site, thoracic/not thoracic | 18/31 | 15/23 | 3/8 | 0.701 |
Tumor site, lumbar/not lumbar | 16/33 | 12/26 | 4/7 | > 0.999 |
Visceral metastasis, no/yes | 28/21 | 20/18 | 8/3 | 0.401 |
Primary tumor, lung/not lung | 23/26 | 20/18 | 3/8 | 0.138 |
Primary tumor, liver/not liver | 7/42 | 5/33 | 2/9 | > 0.999 |
Primary tumor, esophageal/not esophageal | 1/48 | 0/38 | 1/10 | 0.505 |
Primary tumor, kidney/not kidney | 3/46 | 1/37 | 2/9 | 0.238 |
Primary tumor, breast/not breast | 8/41 | 7/31 | 1/10 | 0.784 |
Primary tumor, prostate/not prostate | 5/44 | 4/34 | 1/10 | > 0.999 |
Primary tumor, thyroid/not thyroid | 2/47 | 1/37 | 1/10 | 0.930 |
Treatment-related factors | ||||
Preoperative (2 weeks) oral analgesics (pregabalin or gabapentin), no/yes | 9/40 | 6/32 | 3/8 | 0.672 |
Surgery for primary tumor, no/yes | 30/19 | 25/13 | 5/6 | 0.386 |
Preoperative embolism, no/yes | 37/12 | 28/10 | 9/2 | 0.877 |
Preoperative radiotherapy, no/yes | 45/4 | 36/2 | 9/2 | 0.452 |
Preoperative chemotherapy, no/yes | 41/8 | 32/6 | 9/2 | > 0.999 |
Preoperative targeted therapy, no/yes | 46/3 | 36/2 | 10/1 | > 0.999 |
Operation mode, TES/PSRS | 26/23 | 20/18 | 6/5 | 0.911 |
Surgical approach, posterior/combined | 41/8 | 33/5 | 8/3 | 0.514 |
Internal fixed quantity, ≤ 6 / > 6 | 8/41 | 7/31 | 1/10 | 0.784 |
Artificial implant, bone cement/artificial vertebral body or titanium mesh | 23/26 | 15/23 | 8/3 | 0.052 |
Intraoperative chemotherapy, no/yes | 6/43 | 6/32 | 0/11 | 0.376 |
Intraoperative blood loss, ≤ 2000 mL/ > 2000 mL | 45/4 | 34/4 | 11/0 | 0.619 |
Operation time, ≤ 4 h/ > 4 h | 15/34 | 13/25 | 2/9 | 0.519 |
Postoperative (at 6-month follow-up) oral analgesics (pregabalin or gabapentin), no/yes | 44/5 | 34/4 | 10/1 | > 0.999 |
Postoperative radiotherapy, no/yes | 23/26 | 18/20 | 5/6 | 0.911 |
Postoperative chemotherapy, no/yes | 26/23 | 18/20 | 8/3 | 0.138 |
Postoperative targeted therapy, no/yes | 42/7 | 32/6 | 10/1 | 0.944 |
Postoperative complications, no/yes | 41/8 | 31/7 | 10/1 | 0.784 |
Spinal instability neoplastic score (SINS), ≤ 12/ > 12 | 41/8 | 32/6 | 9/2 | > 0.999 |
Epidural spinal cord compression (ESCC) scale value decreased, ≤ 1/ > 1 | 20/29 | 19/19 | 1/10 | 0.037 |