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Table 1 Demographic and clinicopathologic data of the patients with or without postoperative chemotherapy

From: Does postoperative chemotherapy improve overall survival of patients with ypT1-2N0 cancer?

Variable

All cohort

pCHT

no pCHT

P value†

n = 134

n = 56

n = 78

Age (years)

   

0.367‡

 Mean (SD)

54.2 (10.8)

53.4 (11.5)

54.8 (10.2)

 

Gender

   

0.519

 Female

57 (42.5%)

22 (39.3%)

35 (44.9%)

 

 Male

77 (57.5%)

34 (60.7%)

43 (55.1%)

 

BMI

   

0.672‡

 Mean (SD)

21.0 (5.7)

21.4 (5.3)

20.7(6.2)

 

Tumor size (cm)

   

0.245‡

 Mean (SD)

3.9 (2.0)

4.1 (1.9)

3.8 (2.1)

 

Clinical T stage

   

0.170

 cT2

58 (43.3%)

19 (33.9%)

39 (50.0%)

 

 cT3

57 (42.5%)

27 (48.2%)

30 (38.5%)

 

 cT4

19 (14.2%)

10 (17.9%)

9 (11.5%)

 

Clinical nodal status

   

0.601

 cN−

70 (52.2%)

31 (55.4%)

39 (50.0%)

 

 cN+

64 (47.8%)

25 (44.6%)

39 (50.0%)

 

NACT regimen

   

0.625

 SOX

114 (85.1%)

49 (87.5%)

65 (83.3%)

 

 XELOX

20 (14.9%)

7 (12.5%)

13 (16.7%)

 

No. of NACT cycles

   

0.381

 2

15 (11.2%)

8 (14.3%)

7 (9.0%)

 

 3

36 (26.9%)

17 (30.4%)

19 (24.4%)

 

 4

83 (61.9%)

31 (55.3%)

52 (66.6%)

 

Tumor location

   

0.860

 Upper third

39 (29.1%)

16 (28.6%)

23 (29.5%)

 

 Middle third

44 (32.8%)

20 (35.7%)

24 (30.8%)

 

 Lower third

51 (38.1%)

20 (35.7%)

31 (39.7%)

 

Type of resection

   

0.502

 Subtotal

72 (53.7%)

32 (57.1%)

40 (51.3%)

 

 Total

62 (46.3%)

24 (42.9%)

38 (48.7%)

 

Lauren type

   

0.138

 Intestinal

86 (64.2%)

40 (71.4%)

46 (59.0%)

 

 Diffuse/mixed

48 (35.8%)

16 (28.6%)

32 (41.0%)

 

Differentiation

   

0.934

 Well/moderate

88 (65.7%)

37 (66.1%)

51 (65.4%)

 

 Poor

46 (34.3%)

19 (33.9%)

27 (34.6%)

 

Signet ring cell

   

0.110

 No

98 (73.1%)

45 (80.4%)

53 (67.9%)

 

 Yes

36 (26.9%)

11 (19.6%)

25 (32.1%)

 

Pathological T stage

   

0.370

 ypT1

51 (38.1%)

24 (42.9%)

27 (34.6%)

 

 ypT2

83 (61.9%)

32 (57.1%)

51 (65.4%)

 

No. of lymph nodes

    

 Mean (SD)

29 (10)

28 (9)

30(12)

0.332‡

Lymphovascular invasion

   

0.153

 No

80 (59.7%)

29 (51.8%)

51 (65.4%)

 

 Yes

54 (40.3%)

27 (48.2%)

27 (34.6%)

 

Pathological response (CAP)

   

0.316

 CAP 0

23 (17.2%)

12 (21.4%)

11 (14.1%)

 

 CAP 1

30 (22.4%)

11 (19.6%)

19 (24.4%)

 

 CAP 2

41 (30.6%)

20 (35.7%)

21 (26.9%)

 

 CAP 3

40 (29.8%)

13 (23.2%)

27 (34.6%)

 
  1. pCHT postoperative chemotherapy, SD standard deviation, BMI body mass index, NACT neoadjuvant chemotherapy, yp pathological status after neoadjuvant chemotherapy, CAP College of American Pathologists
  2. †χ2 test, except
  3. ‡Student’s t test