Table 2 Comparison between patients with disseminated disease and patients without disseminated disease after incidental GBC
From: The diagnostic value of staging laparoscopy in gallbladder cancer: a nationwide cohort study
Characteristicsa | DD-group (N = 22) | Non-DD group (N =85) | p-value Univariable | p-value Multivariable | 95% CI | OR |
|---|---|---|---|---|---|---|
Age, years, median (range) | 64 (49–81) | 63 (36–81) | 0.631 | |||
Gender | ||||||
Female | 19 (86.4%) | 60 (70.6%) | 0.134 | |||
Male | 3 (13.6%) | 25 (29.4%) | ||||
Symptoms | ||||||
Jaundice | 2 (9.1%) | 0 (0.0%) | ||||
Abdominal pain | 5 (22.7%) | 18 (21.2%) | 0.425 | |||
Weight loss | 0 (0.0%) | 3 (3.5%) | ||||
Cholecystitis | 12 (54.5%) | 18 (21.2%) | 0.002 | 0.006 | 1.51–11.91 | 4.25 |
Cholecystolithiasis | 8 (36.4%) | 36 (42.4%) | 0.582 | |||
Primary sclerosing cholangitis | 0 (0.0%) | 4 (4.7%) | 0.300 | |||
Gallbladder polyp | 0 (0.0%) | 4 (4.7%) | 0.300 | |||
Type of surgery | ||||||
Laparoscopic cholecystectomy | 16 (72.7%) | 69 (81.2%) | ||||
Open cholecystectomy | 5 (22.7%) | 15 (17.6%) | 0.210 | |||
Other | 1 (4.5%) | 1 (1.2%) | ||||
Perioperative bile spill | 5 (22.7%) | 22 (25.9%) | 0.761 | |||
R1/R2 resection | 15 (68.1%) | 29 (34.1%) | 0.004 | 0.010 | 1.39–11.19 | 3.94 |
Time between primary surgery and re-resection, days, median (range) | 83 (5–132) | 72 (0–164) | 0.643 | |||
pT stage | ||||||
1 | 1 (4.5%) | 11 (12.9%) | ||||
2 | 12 (54.5%) | 62 (72.9%) | 0.015 | 0.562 | 0.55–3.02 | 1.29 |
3 | 9 (40.9%) | 12 (14.1%) | ||||
pN stage | ||||||
0 | 2 (9.1%) | 28 (32.9%) | ||||
1 | 6 (27.2%) | 14 (16.5%) | 0.074 | 0.516 | 0.77–1.68 | 1.14 |
X | 14 (63.6%) | 43 (50.6%) | ||||
Perineural invasion | 10 (45.5%) | 19 (22.4%) | 0.030 | 0.110 | 0.83–6.30 | 2.29 |
Vascular invasion | 8 (36.4%) | 19 (22.4%) | 0.178 | |||