Fig. 1

The expression levels of BRIP1 gene in different tumors and pathological stages. a The transcription levels of BRIP1 in different types of human cancers (ONCOMINE). The cell number represents the dataset number that meets all the thresholds with the color blue for under-expression and color red for over-expression. Cell color is determined by the best gene rank percentile for the analyses within the cell. b The expression status of the BRIP1 gene in different cancers or specific cancer subtypes was analyzed through TIMER2. *P<0.05; **P<0.01; ***P<0.001. c For the type of DLBC, SARC, THYM, and UCS in the TCGA project, the corresponding normal tissues of the GTEx database were included as controls. The box plot data were supplied. *P <0.05. d Representative immunohistochemistry images of BRIP1 in breast cancer, lung cancer, colorectal cancer, liver cancer, prostate cancer, and their corresponding normal tissues (Human Protein Atlas). e Based on the TCGA data, the expression levels of the BRIP1 gene were analyzed by the main pathological stages (stage I, stage II, stage III, and stage IV) of ACC, BRCA, SKCM, KIRP, LIHC, LUSC, KIRC, THCA, UCS, KICH, and OV. Log2 (TPM+1) was applied for the log-scale