Table 2 Survival of GBC patients, results of Kaplan-Meier, and log-rank test

Total

24.4

8.5

4.5

Age

26–45

40.0

17.8

6.7

5.215

0.022*

46–65

19.1

5.3

3.8

Gender

Female

23.0

7.1

4.0

0.012

0.911

Male

28.0

12.0

6.0

Region

Rural

27.0

10.1

5.4

5.630

0.018*

Urban

10.7

0.0

0.0

Dietary habit

Vegetarian

25.3

10.3

5.5

1.147

0.284

Nonvegetarian

20.3

0.0

0.0

Tobacco chewing

Non-chewer

27.2

8.7

2.2

0.080

0.777

Chewer

21.4

8.3

7.1

Jaundice

Absent

34.7

12.5

6.9

9.385

0.002*

Present

17.3

5.8

2.9

Gallstones

Absent

58.8

27.5

13.7

33.987

< 0.0001*

Present

10.4

0.8

0.8

Liver infiltration

Absent

55.9

17.6

5.9

10.837

0.001*

Present

16.9

6.3

4.2

Any chronic disease

Absent

25.9

9.8

4.9

0.341

0.559

Present

18.2

3.0

3.0

Histology

Adenocarcinoma

22.8

7.6

5.1

0.202

0.653

Non-adenocarcinoma

38.9

16.7

0

Grade

I/II

34.3

13.3

6.7

10.149

0.001*

III/IV

9.9

1.4

1.4

Tumor location

Fundus

28.3

10.4

3.8

1.300

0.254

Body-neck

18.6

5.7

5.7

Clinical stage

I/II

56.2

18.8

6.2

8.159

0.004*

III/IV

17.4

6.2

4.2

T stage

T1/T2

54.0

26.0

16.0

29.860

< 0.0001*

T3/T4

12.7

1.6

0.0

N stage

N0

38.6

14.5

8.4

14.520

< 0.0001*

N1/N2

11.8

3.2

1.1

M stage

M0

57.4

22.1

11.8

62.191

< 0.0001*

M1

3.7

0.0

0.0

Surgery

No

13.3

0.0

0.0

39.755

< 0.0001*

Yes

61.0

36.6

19.5

Radiation

No

19.2

3.8

0.6

23.486

< 0.0001*

Yes

65.0

45.0

35.0

Chemotherapy

No

18.5

11.1

3.7

0.213

0.645

Yes

25.5

8.1

4.7

Chemotherapy regimens

Gemcitabine + cisplatin

24.3

7.9

3.9

2.454

0.293

Gemcitabine + carboplatin

18.8

6.2

6.2

Nill

37.5

25.0

12.5