Table 6 Multivariate Cox regression model for OS considering reoperation as a time-dependent covariate in 117 patients
Variable of interest | No. of events/no. of patients (n = 117) | HR (CI 95%) | p value |
|---|---|---|---|
Reintervention as a time-dependent covariate | 0.017 | ||
Reintervention | 29/33 | 1.76 (1.10–2.80) | |
No reintervention | 82/84 | 1 | |
Chemotherapy | 0.687 | ||
Complete Stupp | 63/68 | 0.87 (0.46–1.65) | |
Incomplete Stupp | 47/49 | 1 | |
ECOG 1 | 0.185 | ||
Asymptomatic/mild | 94/100 | 0.68 (0.39–1.19) | |
Symptomatic | 17/17 | 1 | |
ECOG 2 | 0.011 | ||
Asymptomatic/mild | 67/72 | 0.57 (0.37–0.88) | |
Symptomatic | 44/45 | 1 | |
PFS (months) | 0.012 | ||
≥ 10 | 54/59 | 0.43 (0.22–0.83) | |
< 10 | 57/58 | 1 |