Variable of interest | No. of events/no. of patients (n = 117) | HR (CI 95%) | p value |
---|---|---|---|
Age (years) | 0.351 | ||
< 58 | 53/56 | 0.83 (0.57–1.03) | |
≥ 58 | 58/61 | 1 | |
Comorbidities | 0.595 | ||
Absent | 80/85 | 0.89 (0.58–1.35) | |
Present | 31/32 | 1 | |
Volume (cm3) | 0.270 | ||
< 24 | 56/58 | 0.80 (0.55–1.18) | |
≥ 24 | 55/59 | 1 | |
Surgical assistants | 0.961 | ||
Advanced | 44/49 | 0.93 (0.57–1.52) | 0.782 |
Navigation | 41/42 | 0.94 (0.57–1.55) | 0.961 |
None | 26/26 | 1 | |
Complications | 0.741 | ||
None | 82/87 | 0.93 (0.60–1.42) | |
Any | 29/30 | 1 | |
Resection at first surgery | 0.179 | ||
GTR | 83/87 | 0.74 (0.47–1.14) | |
STR | 28/30 | 1 | |
ECOG 1 | 0.096 | ||
Asymptomatic/mild | 94/100 | 0.64 (0.38–1.08) | |
Symptomatic | 17/17 | 1 | |
First surgery date | 0.148 | ||
Recent (2012–2019) | 77/83 | 0.74 (0.49–1.11) | |
Old (2005–2011) | 34/34 | 1 | |
Chemotherapy | < 0.001 | ||
Complete Stupp | 63/68 | 0.48 (0.32–0.71) | |
Incomplete Stupp | 48/49 | 1 | |
ECOG 2 | 0.002 | ||
Asymptomatic/mild | 67/72 | 0.54 (0.37–0.80) | |
Symptomatic | 44/45 | 1 | < 0.001 |
PFS (months) | |||
≥ 10 | 54/59 | 0.39 (0.26–0.58) | |
< 10 | 57/58 | 1 | |
Treatment groups | 0.006 | ||
Reintervention | 29/33 | 0.54 (0.34–0.83) | |
Chemotherapy | 82/84 | 1 |