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Table 4 Correlations of the SWI/SNF complex with clinicopathological characters

From: Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma

  

SWI/SNF complex

 

Variables

Total (n = 21)

Deficient (n = 14)

Intact (n = 7)

P value

Sex

   

1

 Female

4 (19.05)

3 (21.43)

1 (14.29)

 

 Male

17 (80.95)

11 (78.57)

6 (85.71)

 

Age

   

0.2941

 Median (IQR)

68 (61,70)

65.5 (58,70)

70 (66.5,72)

 

CellMorphology

   

1

 NonRhabdoid

13 (61.9)

9 (64.29)

4 (57.14)

 

 Rhabdoid

8 (38.1)

5 (35.71)

3 (42.86)

 

DifferentiationType

   

0.6424

 Dedifferentiation

12 (57.14)

7 (50)

5 (71.43)

 

 Undifferentiated

9 (42.86)

7 (50)

2 (28.57)

 

Site

   

1

 Gastric antrum

13 (61.9)

8 (57.14)

5 (71.43)

 

 Gastric body

7 (33.33)

5 (35.71)

2 (28.57)

 

 Gastric fundus

1 (4.76)

1 (7.14)

0 (0)

 

Size (cm)

   

0.9099

 Mean (SD)

7.04 (2.89)

6.99 (2.66)

7.14 (3.52)

 

T_Stage

   

0.6244

 T1&T2

5 (23.81)

4 (28.57)

1 (14.29)

 

 T3&T4

16 (76.19)

10 (71.43)

6 (85.71)

 

N_Stage

   

1

 N-

9 (42.86)

6 (42.86)

3 (42.86)

 

 N+

12 (57.14)

8 (57.14)

4 (57.14)

 

M_Stage

   

1

 M0

20 (95.24)

13 (92.86)

7 (100)

 

 M1

1 (4.76)

1 (7.14)

0 (0)

 

TNM_Stage

   

1

 I&II

9 (42.86)

6 (42.86)

3 (42.86)

 

 III&IV

12 (57.14)

8 (57.14)

4 (57.14)

 

VascularInvasion

   

0.1736

 No

8 (38.1)

7 (50)

1 (14.29)

 

 Yes

13 (61.9)

7 (50)

6 (85.71)

 

Necrosis

   

0.3371

 No

14 (66.67)

8 (57.14)

6 (85.71)

 

 Yes

7 (33.33)

6 (42.86)

1 (14.29)

 

P53

   

0.3615

 Mutate

11 (52.38)

6 (42.86)

5 (71.43)

 

 Wild

10 (47.62)

8 (57.14)

2 (28.57)

 

PD-L1

   

0.3972

 Negative

12 (57.14)

9 (64.29)

3 (42.86)

 

 Positive

9 (42.86)

5 (35.71)

4 (57.14)

 

MMR

   

0.6244

 dMMR

5 (23.81)

4 (28.57)

1 (14.29)

 

 pMMR

16 (76.19)

10 (71.43)

6 (85.71)

 

CSCphenotype

   

0.0158

 Negative

9 (42.86)

3 (21.43)

6 (85.71)

 

 Positive

12 (57.14)

11 (78.57)

1 (14.29)

 
  1. IQR interquartile range, SD standard deviation, MMR mismatch repair proteins, dMMR MMR deficient, pMMR MMR proficient, CSC cancer stem cells