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Table 1 Surgical characteristics and pre-operative laboratory parameters in 72 patients with primary retroperitoneal liposarcoma

From: Sarcopenia is associated with worse surgical complications but not relapse-free survival and overall survival in patients with retroperitoneal liposarcoma

Variables

Total N = 72

Sarcopenia

Non-sarcopenia

P value

Gender

   

0.086

 Male

47

24

23

 

 Female

25

18

7

 

Age (years) (mean ± SD)

57.49 ± 10.92

59.13 ± 11.64

55.3 ± 9.64

0.148

Symptoms

   

0.905

 Yes

33

19

14

 

 No

39

23

16

 

Histologic subtypes

   

0.331

 Well-differentiated (WDLPS)

47

25

22

 

 Myxoid/round cell (MLPS)

6

4

2

 

 Dedifferentiated (DDLPS)

18

13

5

 

 Pleomorphic (PLPS)

1

0

1

 

FNCLCC

   

0.334

 Grade1

31

19

12

 

 Grade2

27

13

14

 

 Grade3

14

10

4

 

Tumor burden, cm median (IQR)

20, 15–29.5

20, 13–29

20, 15–30

0.402

Combined-organ resection

   

0.371

 Yes

54

32

22

 

 No

18

10

8

 

Operation duration, hours median (IQR)

4.0, 3.0–5.0

4.0, 3.0–5.0

4.0, 2.0–5.0

0.959

Estimated blood loss, mL median (IQR)

400, 200–700

500, 100–825

300, 200–500

0.160

Blood transfusion

   

0.213

 Yes

20

14

6

 

 No

52

28

24

 

ICU stay

   

0.468

 Yes

49

30

19

 

 No

23

12

11

 

Complications

   

0.362

 Yes

26

17

9

 

 No

46

25

21

 

Clavien-Dindo classification

   

0.011*

 ≤ 2

64

34

30

 

 > 2

8

8

0

 

Postoperative hospital stays, days median (IQR)

15, 12–22.75

16, 13–24

14, 9–21

0.093

BMI (mean ± SD)

23.48 ± 3.78

22.48 ± 3.79

24.9 ± 3.35

0.007*

ALB, g/L (mean ± SD)

38.51 ± 5.77

38.44 ± 5.74

38.61 ± 5.91

0.904

PALB, g/L (mean ± SD)

0.21 ± 0.08

0.20 ± 0.08

0.22 ± 0.08

0.375

A/G (mean ± SD)

1.46 ± 0.39

1.47 ± 0.39

1.46 ± 0.39

0.908

Hb, g/L (mean ± SD)

124.42 ± 17.01

120.76 ± 16.35

129.43 ± 16.88

0.033*

SCr,μmol/L (mean ± SD)

74.3 ± 18.15

74.09 ± 20.27

74.61 ± 15.07

0.907

SMA, cm2 (mean ± SD)

111.81 ± 28.81

95.47 ± 17.39

134.67 ± 26.02

0.000

SMI (mean ± SD)

40.64 ± 8.85

35.03 ± 4.79

48.5 ± 7.05

0.000

PMA, cm2 (mean ± SD)

14.23 ± 5.06

12.28 ± 3.66

16.95 ± 5.54

0.000

PMI (mean ± SD)

5.15 ± 1.63

4.49 ± 1.14

6.08 ± 1.77

0.000

Fat area, cm2 (mean ± SD)

78.24 ± 46.7

76.26 ± 44.48

80.56 ± 49.86

0.719

  1. BMI body mass index, ALB albumin, PALB pre-albumin, A/G albumin globulin, Hb hemoglobin, SCr serum creatinine, SMA skeletal muscle area, SMI skeletal muscle index, PMA psoas muscle area, PMI psoas muscle index