circRNAs and their relationship with breast cancer: a review

Table 4 Diagnosis efficiency of circRNAs for breast cancer

CircRNA	Expression in BC	Subtype of BC	Sample	AUC	Sensitivity	Specificity	Cut-off	Number of cases	Ref.
circACTN4	↑	non-TNBC	Tissue	0.719	0.7	0.7	12.77	80	[45]
hsa_circ_0001785	↑	–	Plasma	0.771	0.786	0.756	–	20	[43]
hsa_circ_0001785	↑	–	Plasma	0.784	0.764	0.699	0.981	57	[43]
circSEPT9	↑	TNBC	Tissue	0.711	0.633	0.75	1.971	60	[42]
hsa_circ_103110	↑	IDC	Tissue	0.63	0.63	0.63	8.97	51	[79]
hsa_circ_104689				0.61	0.57	0.55	7.67
hsa_circ_104821				0.60	0.57	0.57	6.04
hsa_circ_006054	↓			0.71	0.65	0.69	14.84
hsa_circ_100219				0.78	0.69	0.71	8.95
hsa_circ_406697				0.64	0.63	0.63	14.24
hsa_circ_0001073	↓	–	Tissue	0.9898	0.9242	0.9737	6.68	132	[78]
circVRK1	↓	–	Tissue	0.72	0.617	0.791	0.425	350	[80]

ISSN: 1477-7819