Table 3 circRNAs and clinicopathological features of breast cancer
From: circRNAs and their relationship with breast cancer: a review
CircRNA | Expression in BC | Subtype of BC | Clinicopathological features | Number of cases | Ref. | ||||
|---|---|---|---|---|---|---|---|---|---|
Tumor size and TNM stage | Metastasis | IHC and subtype | Grade | Others | |||||
circSEPT9 | ↑ | TNBC | T, N, TNM |  |  |  |  | 60 | [42] |
hsa_circ_001783 | ↑ | - | T, N, TNM |  | ER, PR, Ki-67, molecular subtype |  |  | 136 | [5] |
circRNF20 (hsa_circ_0087784) | ↑ | - | tumor size | LN |  |  |  | 50 | [6] |
hsa_circ_0005273 | ↑ | – | tumor size, TNM | LN, distant |  |  |  | 120 | [34] |
circACTN4 | ↑ | Non-TNBC | T, N, TNM |  |  |  |  | 240 | [45] |
hsa_circ_0001785 | ↑ | – | TNM | Distant |  | Histological grade |  | 57 | [43] |
circHMCU (hsa_circ_0000247) | ↑ | – | T, N | LN | ER, PR, HER2 | Histological grade |  | 267 | [72] |
circKIF4A (hsa_circ_0007255) | ↑ | TNBC | Tumor size, TNM | LN |  |  |  | 240 | [73] |
circMMP11 (hsa_circ_0062558) | ↑ | – | TNM | LN |  |  |  | 113 | [74] |
circEPSTI1 (hsa_circ_000479) | ↑ | TNBC | Tumor size, TNM | LN |  |  |  | 240 | [75] |
circLARP4 | ↑ | – | Tumor size, T, N, TNM |  |  |  |  | 283 | [76] |
circPLK1 (has_circ_0038632) | ↑ | TNBC | Tumor size, TNM | LN |  |  |  | 240 | [75] |
circRNA_100395 | ↓ | – | T |  |  |  |  | 52 | [77] |
hsa_circ_0025202 | ↓ | HR-positive BC |  | LN |  | Histological grade, |  | 230 | [39] |
hsa_circ_0001073 | ↓ | - | Tumor size | LN |  |  | age | 132 | [78] |